Pattaya Medical Knowledge

The Role of GLP-1 Therapies in Treating Obesity: A Comprehensive Overview

By Dr.Kijakarn Junda, 2025

Introduction Obesity has become a global public health crisis, affecting over 1 billion people and driving significant morbidity, mortality, and economic burden (Celletti et al., 2025). The World Health Organization (WHO) has recognized obesity as a chronic, relapsing disease, emphasizing the need for lifelong care and integrated treatment strategies. Among the emerging solutions, glucagon-like peptide-1 (GLP-1) therapies have gained prominence due to their ability to promote weight loss and improve metabolic health.

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Post-Exposure Prophylaxis (PEP) for HIV: Detailed Overview

Definition: PEP is a 28-day course of HIV medicines taken to prevent HIV infection after potential exposure. It must be started within 72 hours (3 days) of exposure for the best chance of effectiveness.

When to Start:

Critical Window: Initiate PEP as soon as possible after exposure, ideally within hours. Even a delay of 72 hours may significantly reduce its effectiveness.

Who Needs PEP?