10 FAQ for HIV PEP

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Here are 10 frequently asked questions (FAQ) about HIV Post-Exposure Prophylaxis (PEP):

  1. What is HIV PEP?
  2. PEP stands for Post-Exposure Prophylaxis, which is emergency HIV prevention treatment taken within 72 hours after potential exposure to HIV. It involves taking antiretroviral medications to prevent infection.
  1. Who should take PEP?
  2. PEP is recommended for individuals who may have been exposed to HIV, such as through unprotected sex, sharing needles, or occupational exposures like needle-stick injuries (CMDT, 2021).
  1. When should PEP be started?
  2. PEP should be started as soon as possible, ideally within hours, but no later than 72 hours after exposure to be effective (CMDT, 2021).
  1. How long should PEP be taken?
  2. PEP typically involves taking antiretroviral medications for 28 days. It is crucial to complete the full course even if you feel well (CMDT, 2021).
  1. What medications are used in PEP?
  2. Common PEP regimens include a combination of antiretroviral drugs such as tenofovir disoproxil fumarate, emtricitabine, and either raltegravir or dolutegravir (CMDT, 2021).
  1. Can PEP be 100% effective?
  2. PEP is highly effective when started promptly and taken correctly, but it is not 100% guaranteed. The effectiveness depends on factors like the timing of initiation and adherence to the regimen.
  1. What are the side effects of PEP?
  2. Common side effects may include nausea, fatigue, headaches, and diarrhea. Severe side effects are rare but can include liver toxicity. Always consult a healthcare provider if side effects are severe.
  1. Can PEP be taken if I am pregnant or breastfeeding?
  2. Yes, but it should be done under medical supervision to ensure safety for both the mother and the baby. The benefits of preventing HIV often outweigh the risks (CMDT, 2021).
  1. What if I need PEP more than once?
  2. It is possible to take PEP more than once if there are repeated exposures, but it is essential to discuss this with a healthcare provider to assess the risks and benefits.
  1. Can PEP be used as regular protection against HIV?
    • No, PEP is not a substitute for regular prevention methods like condoms, PrEP (Pre-Exposure Prophylaxis), or abstaining from high-risk behaviors. It is only for emergency situations (CMDT, 2021).

Source Citation:

  • CMDT (Current Medical Diagnosis and Treatment). (2021). Chapter 42, HIV Infection.