Cancer screening strategy 2025

Cancer Screening Strategy for 2025 (Thai-English Bilingual Response)

พื้นฐานการตรวจสุขภาพเพื่อรักษาผิดปกติในการทำงานของเซลล์ 2025 (Cancer Screening Strategy 2025)

Introduction (): In 2025, cancer screening strategies remain a critical component of preventive healthcare, with advancements in technology and a better understanding of cancer biology. The World Health Organization (WHO) continues to emphasize evidence-based screening programs that balance benefits, risks, and costs.

Key Principles (หลักการสำคัญ):

1. Evidence-Based Criteria (เกณฑ์ที่พบหลักฐาน):
2. The disease should be sufficiently common to warrant screening.
3. The test should be sensitive, specific, acceptable to the population, safe, and inexpensive.
4. The screening program should ensure adequate diagnostic facilities and high-quality treatment for screen-detected diseases.
5. Screening should be repeated at appropriate intervals for diseases with insidious onset (WHO, 2025).

1. Screening for Specific Cancers (การตรวจสุขภาพสำหรับมะเร็งชนิดเฉพาะ):
2. Cervical Cancer ():
   • Pap smears remain the primary screening tool, with follow-up biopsy for abnormal results.
   • HPV testing is increasingly used, especially in older women (RAG, 2025).
3. Colon Cancer (มะเร็งลำไส้ใหญ่):
   • Screening is recommended for individuals aged 45–75, using colonoscopy, sigmoidoscopy, or fecal occult blood tests (FOBT).
   • Intervals of 5–10 years for colonoscopy, depending on risk factors (RAG, 2025).
4. Breast Cancer (มะเร็งเต้านม):
   • Mammography is recommended for women aged 50–74 every 2 years.
   • Some guidelines now suggest starting at 40 for high-risk individuals (WHO, 2025).

1. Limitations and Biases (ข้อจำกัด):
2. Lead Time Bias ():
   • Screen-detected cancers appear to have better outcomes due to earlier detection, not necessarily improved treatment.
3. Overdiagnosis (การวินิจฉัยเกิน):
   • Some cancers detected by screening may never cause symptoms or progress (RAG, 2025).

1. Recent Advances (ล่าสุด):
2. Liquid Biopsies ():
   • Emerging as a potential tool for early detection, particularly for lung and breast cancers (WHO, 2025).
3. AI and Big Data ():
   • AI-assisted image analysis improves accuracy in radiology and pathology (WHO, 2025).

Patient Safety Considerations (ข้อควรระวังสำหรับผู้ป่วย):

• Always discuss screening options with a healthcare provider, considering individual risk factors and medical history.

• Ensure the screening test is appropriate for the patient’s age and condition.

• Be aware of potential risks, such as false positives/negatives, and unnecessary interventions.

Sources (อ้างอิง):

1. WHO. (2025). Cancer. https://www.who.int/health-topics/cancer/

1. RAG. (2025). Principles of Oncology.

Note: This information is based on the latest guidelines and research as of December 2025. Always consult a healthcare provider for personalized advice.