Category: migraine
Migraine treatment in pregnancy
First-Line Treatment:
- Acetaminophen (Paracetamol):
- Safe in pregnancy (FDA category B).
- Dose: 500
How to avoid migraine?
Identify and Avoid Triggers:
- Common triggers: stress, lack of sleep, certain foods (e.g., aged cheese, chocolate
Drugs to prevent Migraine
Beta-blockers (e.g., propranolol, metoprolol)
- Rationale: Reduce sympathetic nervous system activity, which may p
10 faq of migraine
- What is migraine?
- A primary headache disorder characterized by recurrent episodes of moderate to severe headache,
Rare presentation of migraine
Migraine with acute confusional state (ACS):
- Rare, often seen in children or elderly patients.
- Presents with
migaine with basilar artery
Basilar Artery Migraine (BAM):
- Definition: A subtype of migraine with aura, characterized by symptoms refera
migrainous infarction case
Migrainous Infarction (MI):
- Definition: Rare complication of migraine with aura, leading to ischemic stroke.
Novel medicine for migraine
CGRP Antagonists (Gepants):
- Ubrogepant (Ubrelya): Approved for acute treatment; blocks CGRP receptor.
- **
Injection for migraine
5-HT1B/1D receptor agonists (triptans) for acute migraine:
- Subcutaneous (SC) route: Sumatriptan, Rizatriptan, Zo
Ditans in Migraine
Mechanism of Action:
- Ditans are selective 5-HT1F receptor agonists.
- Unlike triptans, they do not cause vasoc
What is Gepants
Gepants are a class of small-molecule, orally administered calcitonin gene-related peptide (CGRP) receptor antagonis
...CGRP Antagonists in details
Mechanism of Action:
- CGRP antagonists (gepants) block the calcitonin gene-related peptide (CGRP) receptor, preve
New treatment of Migraine
CGRP Antagonists (Small Molecule and Monoclonal Antibodies):
- Small Molecule CGRP Antagonists (Gepants):