Medicines that can cause headache:
- Antidepressants (e.g., tricyclics like amitriptyline, nortriptyline):
- Rationale: These medications can sometimes trigger or worsen headaches, especially if the dose is too high or if the patient is sensitive to them.
- Nonsteroidal anti-inflammatory drugs (NSAIDs, e.g., ibuprofen, naproxen):
- Rationale: While used to treat pain, overuse or high doses can paradoxically cause headaches.
- Nitrates (e.g., nitroglycerin):
- Rationale: These vasodilators can cause headaches as a side effect due to blood vessel dilation.
- Oral contraceptives (estrogen-containing):
- Rationale: Hormonal changes can trigger headaches in some individuals.
- Calcium channel blockers (e.g., verapamil, nifedipine):
- Rationale: These medications can cause headaches due to their vasodilatory effects.
If you suspect a medication is causing your headaches, it’s important to discuss this with your doctor, as adjustments may be needed.